Lizinna is a combined oral contraceptive pill containing norgestimate (250 micrograms) and ethinylestradiol (35 micrograms). It prevents pregnancy by stopping ovulation, thickening cervical mucus to block sperm, and thinning the lining of the womb to reduce implantation.
Each pack contains 21 active tablets. When taken correctly, Lizinna is over 99% effective at preventing pregnancy.
Lizinna Tablets
From: £9.99
Description
Directions for Use
- Take one tablet daily at the same time each day.
- Take tablets for 21 days, followed by a 7-day tablet-free break.
- Start the next pack after 7 days, even if bleeding continues.
- A withdrawal bleed usually occurs during the 7-day break.
Starting Lizinna:
- Start on Day 1 of your period for immediate protection.
- If starting between Days 2–5, use additional contraception for 7 days.
Missed tablet:
- One missed tablet: take as soon as remembered and continue as normal.
- Two or more missed tablets: take the most recent missed tablet immediately, continue as normal and use extra contraception for 7 days.
- If pills are missed in week 1 and unprotected sex occurred, seek urgent medical advice.
Vomiting within 2–3 hours of taking a tablet or severe diarrhoea may reduce protection — take another tablet and follow missed pill advice.
After childbirth:
- Can usually be started from 21 days after delivery if not breastfeeding.
- If breastfeeding, seek medical advice before use.
Side Effects
Serious side effects (seek urgent medical help):
- Blood clots in the leg, lungs, heart, brain, eye or abdominal organs.
- Sudden chest pain, breathlessness, leg swelling, or weakness on one side of the body.
- Severe allergic reactions (swelling of face, lips, tongue or throat).
- Severe liver problems (yellowing of skin or eyes, severe abdominal pain).
- Possible signs of breast cancer (new lumps, nipple changes).
Common side effects:
- Headache or migraine
- Nausea, vomiting, diarrhoea
- Breast pain or tenderness
- Mood changes or depression
- Weight gain
- Irregular bleeding or spotting in early months
Report side effects via the MHRA Yellow Card Scheme.
Warnings
Do NOT take Lizinna if you:
- Are pregnant.
- Have ever had blood clots, stroke, heart attack or angina.
- Have migraine with aura.
- Have severe liver disease or breast cancer.
- Have very high blood pressure or severe diabetes with complications.
- Are taking certain Hepatitis C treatments (ombitasvir/paritaprevir/ritonavir, glecaprevir/pibrentasvir, sofosbuvir/velpatasvir/voxilaprevir).
Speak to a clinician before use if you:
- Are over 35 and smoke.
- Are overweight (BMI >30).
- Have diabetes, high blood pressure, epilepsy, lupus, Crohn’s disease or gallbladder disease.
- Have a history of depression, migraines, varicose veins or blood clots.
Important information:
- Slightly increases the risk of blood clots and breast/cervical cancer.
- Does not protect against STIs — condoms should be used.
- Some medicines and herbal remedies (e.g. epilepsy medicines, rifampicin, St John’s Wort) can reduce effectiveness.
Faqs
How effective is Lizinna?
Over 99% effective with correct use.
Will Lizinna affect my periods?
Periods usually become regular, lighter and less painful.
Can I get pregnant after stopping Lizinna?
Yes — fertility usually returns quickly.
What should I do if I miss a pill?
Take the most recent missed pill immediately and use extra contraception for 7 days if more than one pill is missed.
Can I take Lizinna after having a baby?
Yes, from 21 days after delivery if not breastfeeding. Breastfeeding women should seek medical advice.
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