Nitrofurantoin 100mg MR Capsules
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Nitrofurantoin 100mg MR Capsules

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Description

Nitrofurantoin is an antibiotic used to treat and prevent urinary tract infections (UTIs) caused by susceptible bacteria. It works by killing the bacteria responsible for infection in the bladder, kidneys, or urinary tract.

The 100mg modified-release (MR) capsules are designed to release the medicine slowly, maintaining effective levels in the urine for longer periods. The 50mg tablets are typically used for shorter courses or for preventive treatment, depending on clinical need.

Nitrofurantoin is effective against a wide range of bacteria commonly found in urinary infections and is often prescribed as a first-line treatment for uncomplicated cystitis in women.

Directions for Use
  • Always take Nitrofurantoin exactly as prescribed by your healthcare professional.
  • For 100mg MR capsules: Usually one capsule twice daily (every 12 hours) for 3 to 7 days.
  • For 50mg tablets: Typically one tablet four times daily with food or milk.
  • Swallow the tablets or capsules whole with water.
  • Take Nitrofurantoin with or after meals to improve absorption and reduce the risk of stomach upset.
  • Complete the full course of treatment even if you start feeling better.
  • If you miss a dose, take it as soon as you remember unless it’s nearly time for your next dose. Do not double up to make up for a missed dose.
Side Effects

Like all medicines, Nitrofurantoin can cause side effects, although not everyone experiences them.
Common side effects include:

  • Nausea or vomiting
  • Loss of appetite
  • Headache or dizziness
  • Drowsiness or fatigue
  • Dark yellow or brown urine (this is harmless)

Less common but serious side effects may include:

  • Shortness of breath, cough, or chest pain (possible signs of lung reaction)
  • Yellowing of the skin or eyes (signs of liver problems)
  • Tingling or numbness in the hands or feet (nerve effects)
  • Allergic reactions such as rash, swelling, or difficulty breathing

If you develop breathing problems, persistent cough, fever, or skin rashes, stop taking the medicine and seek medical advice immediately.

Warnings
  • Do not take Nitrofurantoin if you are allergic to it or any of its ingredients.
  • Avoid use if you have severe kidney problems, a history of liver disease, or certain blood disorders such as porphyria.
  • Not recommended in the final stages of pregnancy (at term) or in babies less than three months old.
  • Nitrofurantoin may cause dizziness; do not drive or operate machinery if affected.
  • Your urine may become darker in colour — this is normal and not harmful.
  • If taking for long-term prevention, your healthcare professional may perform regular blood, liver, or kidney function tests.
  • Tell your doctor if you are taking any other medicines, especially antacids containing magnesium trisilicate, quinolone antibiotics, or probenecid, as these can affect Nitrofurantoin’s effectiveness.
Faqs

What is Nitrofurantoin used for?
Nitrofurantoin is used to treat and prevent urinary tract infections (UTIs) such as cystitis, caused by bacteria in the bladder or urinary system.

What is the difference between Nitrofurantoin 100mg MR and 50mg tablets?
The 100mg MR (modified-release) capsules are designed to release the medicine slowly and are usually taken twice daily, while the 50mg tablets are taken four times daily. Both treat bacterial infections in the urinary tract effectively.

How quickly does Nitrofurantoin start working?
Most people begin to feel better within two to three days, but it’s essential to complete the full course prescribed to prevent the infection from returning.

Can I drink alcohol while taking Nitrofurantoin?
Yes, alcohol does not directly interact with Nitrofurantoin, but it’s best to avoid excessive drinking while unwell, as it may delay recovery.

What should I do if I miss a dose?
Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed one — do not take a double dose to make up for it.

Can Nitrofurantoin cause my urine to change colour?
Yes. It may turn dark yellow or brown, which is harmless and disappears once treatment ends.

What should I do if I experience side effects?
If you develop severe shortness of breath, coughing, rash, or yellowing of the skin, stop taking Nitrofurantoin and seek medical attention immediately.

Can Nitrofurantoin be used for kidney infections?
No. Nitrofurantoin is suitable for lower urinary tract infections such as cystitis but is not effective for kidney infections (pyelonephritis).

How can I prevent urinary infections in the future?
Stay well hydrated, urinate regularly, wipe from front to back after using the toilet, and avoid delaying urination. Wearing cotton underwear and maintaining good hygiene can also help reduce the risk of recurrence.

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